| 35. Louisville (22-14) | Rating: 85.20 | SOS Rank: 35 | Proj: 22-14 |
| DATE | OPPONENT | RNK | W-L | Res/Pct | Sco/MOV | QUAL | |
| Sun, | Nov 12 | George Mason | 211 | 16-17 | W | 72-61 | −9 |
| Fri, | Nov 17 | NE Omaha | 289 | 7-22 | W | 87-78 | −16 |
| Tue, | Nov 21 | S Illinois | 139 | 19-13 | W | 84-42 | +28 |
| Fri, | Nov 24 | St Francis PA | 219 | 16-13 | W | 84-72 | −8 |
| Tue, | Nov 28 | at Purdue | 3 | 30-7 | L | 57-66 | +4 |
| Sun, | Dec 3 | Seton Hall | 28 | 22-12 | L | 77-79 | −4 |
| Wed, | Dec 6 | Siena | 295 | 8-24 | W | 86-60 | +1 |
| Sat, | Dec 9 | Indiana | 73 | 16-15 | W | 71-62 | +1 |
| Mon, | Dec 11 | Bryant | 342 | 3-28 | W | 102-59 | +10 |
| Sat, | Dec 16 | *Memphis | 159 | 21-12 | W | 81-72 | −3 |
| Wed, | Dec 20 | Albany NY | 146 | 21-10 | W | 70-68 | −13 |
| Sat, | Dec 23 | Grand Canyon | 116 | 21-12 | W | 74-56 | +6 |
| Fri, | Dec 29 | at Kentucky | 17 | 26-11 | L | 61-90 | −22 |
| Tue, | Jan 2 | Pittsburgh | 201 | 8-24 | W | 77-51 | +7 |
| Sat, | Jan 6 | at Clemson | 15 | 25-10 | L | 69-74 | +2 |
| Wed, | Jan 10 | at Florida St | 25 | 23-12 | W | 73-69 | +9 |
| Sat, | Jan 13 | Virginia Tech | 33 | 21-12 | W | 94-86 | +5 |
| Tue, | Jan 16 | at Notre Dame | 37 | 20-15 | W | 82-78 | +7 |
| Sun, | Jan 21 | Boston College | 75 | 19-16 | W | 77-69 | 0 |
| Wed, | Jan 24 | at Miami FL | 41 | 22-10 | L | 75-78 | 0 |
| Sat, | Jan 27 | Wake Forest | 86 | 11-20 | W | 96-77 | +10 |
| Wed, | Jan 31 | at Virginia | 5 | 31-3 | L | 64-74 | +2 |
| Sat, | Feb 3 | Florida St | 25 | 23-12 | L | 76-80 | −5 |
| Mon, | Feb 5 | Syracuse | 47 | 23-14 | L | 73-78 | −10 |
| Thu, | Feb 8 | Georgia Tech | 114 | 13-19 | W | 77-54 | +11 |
| Sun, | Feb 11 | at Pittsburgh | 201 | 8-24 | W | 94-60 | +22 |
| Sat, | Feb 17 | North Carolina | 8 | 26-11 | L | 76-93 | −14 |
| Wed, | Feb 21 | at Duke | 2 | 29-8 | L | 56-82 | −12 |
| Sat, | Feb 24 | at Virginia Tech | 33 | 21-12 | W | 75-68 | +11 |
| Thu, | Mar 1 | Virginia | 5 | 31-3 | L | 66-67 | +4 |
| Sat, | Mar 3 | at NC State | 45 | 21-12 | L | 69-76 | −5 |
| Wed, | Mar 7 | *Florida St | 25 | 23-12 | W | 82-74 | +10 |
| Thu, | Mar 8 | *Virginia | 5 | 31-3 | L | 58-75 | −9 |
| Tue, | Mar 13 | N Kentucky | 95 | 20-10 | W | 66-58 | −2 |
| Sun, | Mar 18 | MTSU | 58 | 24-8 | W | 84-68 | +11 |
| Tue, | Mar 20 | Mississippi St | 51 | 24-11 | L | 56-79 | −28 |